Thursday, September 23, 2010

Is there ANYTHING  we an eat? I caught the tail end of the Dr. OZ show Tuesday. It was about the things we eat that make us fat. Here are some a few points he made:


 

We blame weight gain on eating too many burgers and burning too little fat, but scientists are discovering that chemicals we’re exposed to everyday could be a big part of the obesity epidemic. Called obesogens, or endocrine disruptors, these natural and man-made chemicals work by altering the regulatory system that controls your weight—increasing the fat cells you have, decreasing the calories you burn, and even altering the way your body manages hunger.

It’s time to fight back. The White House's task force on childhood obesity is tackling obesogens and the Environmental Protection Agency has pumped $20 million into studying them. Here’s what you need to know to wage your own battle on the home front.

How they work
By mimicking the actions of naturally occurring hormones in our bodies or preventing the hormones we produce from acting correctly, endocrine disruptors can:
  • Encourage the body to store fat and re-program cells to become fat cells.
  • Prompt the liver to become insulin resistant, which makes the pancreas pump out more insulin that turns energy into fat all over the body.
  • Prevent leptin (a hormone that reduces appetite) from being released from your fat cells to tell your body you are full.
Where you find them
The short answer: everywhere, particularly because high fructose corn syrup, which can be found in every kind of food, from sodas to yogurt to pretzels, is an obesogen. The ubiquitous, viscous sweet stuff makes your liver insulin resistant and tampers with leptin to increase your hunger, setting up a vicious cycle where you crave more food that is then more easily turned into fat.
Other common places to find obesogens:
  • Meat and farm-raised fish: Research has found that the higher the level of pesticides in your body, the greater your waist circumference and body mass index (BMI). One of the most common places for pesticides to congregate is the fat cells of the animals we eat. A recent study found that farm-raised salmon had 90% more pesticides in it than wild salmon. Experts are also concerned that the hormones used to treat livestock may be causing obesity in people.
  • In your faucets: Pesticides seep deep into the soil and find their way to the water table and into your tap water. The main obesogen in tap water is atrazine. Banned in Europe, but found around the United States, atrazine slows thyroid hormone metabolism. Another culprit found in tap water, tributylin, a fungicide painted on the bottoms of boats, stimulates fat cell production.
  • Cans and water bottles: Bisphenol-A (BPA), a synthetic estrogen used to make plastics hard which has been banned from baby bottles, but is still present in many other plastics (especially sports water bottles) and the lining of most cans, has been shown to increase insulin resistance in animal studies.
  • Nonstick pans and microwave popcorn: Animal studies have shown that early exposure to a chemical used to make items non-stick – Perfluorooctanoic acid (PFOA) – leads to obesity in later life. It also is known to affect thyroid glands, which are important regulators of hormones that control weight. Found mainly in products like Teflon pans, it’s also hidden in microwave popcorn bags and pizza boxes.
  • Shower curtains and air fresheners: Phtalates, chemicals found in vinyl products such as shower curtains and fragrance products such as air fresheners, may lower testosterone and metabolism levels, causing you to gain weight and lose muscle mass. They’re also found in vinyl flooring and industrial-grade plastic wrap used to shrink wrap meat in the grocery store.
How to avoid obesogens:
  • Buy wild fish (such as salmon, which is packed with heart-healthy omega-3 fatty acids) and meat products that are hormone- and antibiotic free.
  • Install a granular activated carbon filter on your faucet to filter out chemicals such as atrazine.
  • Use aluminum water bottles or those that are BPA-free.
  • Steer clear of plastics with the number 3 or 7 on the bottom, which may leach BPA. Instead look for the numbers 1, 2, 4, 5, and 6, which are unlikely to contain BPA.
  • Keep water bottles cool (warm temperatures increase BPA leaching) and never microwave plastic.
  • Eat fewer canned foods. Opt for frozen or fresh instead. Tuna can be found in pouches that do not contain BPA.
  • Get rid of your non-stick pans if possible. If you must use a Teflon pan, never use a metal implement on it that can scratch the surface and release the chemicals inside, and throw away any scratched non-stick pans.
  • Buy meats straight from the butcher counter (instead of pre-packaged) and ask that they wrap them in brown paper.
  • Skip the air fresheners, open the windows, and try a vase of dried lavender instead.

Sunday, September 19, 2010

I recently read an article by Rachel Ehrenberg about cockroaches and locusts that answered the age old question, "Why did God make cockroaches?"


Cockroaches may be nasty bugs, but they could help fight even nastier ones. New research finds that the rudimentary brains of cockroaches and locusts teem with antimicrobial compounds that slay harmful E. coli and MRSA, the antibiotic-resistant staph bacterium. The work could lead to new compounds for fighting infectious diseases in humans.
Extracts of ground-up brain and other nerve tissue from the American cockroach, Periplaneta americana, and desert locust, Schistocerca gregaria, killed more than 90 percent of a type of E. coli that causes meningitis, and also killed methicillin-resistant staph, microbiologist Simon Lee reported September 7 at the Society for General Microbiology meeting at the University of Nottingham in England.
“Some of these insects live in the filthiest places ever known to man,” says Naveed Khan, coauthor of the new study. “These insects crawl on dead tissue, in sewage, in drainage areas. We thought, 'How do they cope with all the bacteria and parasites?’”
Khan and his colleagues became intrigued by insect antimicrobials when they noticed that many soldiers were returning from the Middle East with unusual infections, yet locusts living in the same areas were unperturbed. So the researchers, all from the University of Nottingham, began investigating how the insects ward off disease.
The team ground up various body parts from both cockroaches and locusts that had been reared in the lab and incubated them for two hours with different bacteria. Leaving these mixtures overnight on petri dishes revealed that the extracts from brains and from locust thorax nerve tissue killed nearly 100 percent of the bacteria.
Yet the insect brain extracts didn’t seem to bother human kidney or epithelial cells when grown with them in a lab dish.
Curiously, extracts of insect fat, muscle and blood didn’t bother the bacteria at all. Cockroaches and locusts often eat stuff loaded with microbes, says parasitologist Carl Lowenberger of Simon Fraser University in Burnaby, Canada, so you would think insect guts and blood, which bathes the organs, would have similar antimicrobial activity.
Nine molecules appear to be responsible for the antimicrobial activity in locust tissue, although they have yet to be identified. The team is also still working out the details of the cockroach compounds.
The compounds may work together as a cocktail, Lowenberger says. Insects make hundreds of antimicrobial compounds, and it may be that very high concentrations of those molecules would be required for fighting an infection in humans. But the research “is pretty neat stuff,” he says. And perhaps down the road, the yet-unidentified molecules will prove useful in fighting infections in people.